Pharmaceutical Freeze Dryers China Manufacturer, lyophilizer

FD-P series full function production freeze dryer machine is not only suitable for the freeze-drying of conventional materials in bulk (liquid, paste, solid), but also suitable for the drying of the bottled materials of vials. When preparing for lyophilization, the materials are dispensed into the vials as needed, and the floating cover The bottle cap is lyophilized, and after the drying, the capping mechanism is pressed to press the cap to avoid secondary pollution, re-adsorb moisture, and easy to store for a long time.

Main Features

Shelf pre-freezing function.
Can be filled with nitrogen or inert protect machine after working.
lyophilized automatic control system: procedural programming, both freeze-dried and defrost control procedures.
helf: adopting international advanced welding technology without leak
Lyophilized end point test system: automatic lyophilized end testing parsed end of the drying stage, to ensure that the moisture content of the material to reach the standards.
Vacuum regulator systems: sublimation and vacuum drying process analytical adjustment, avoid special material to foaming & blowing, accelerate lyophilization efficiency.
Pulse backfill system: slow, medium, fast three backfill mode selection, avoiding the issue for the end of the freeze-dried granular material and flocculent inflatable produce effective substances are blown away loss.
Large industrial touch screen, human-computer interaction is good, easy to understand, no instructions are also available for easy operation.
Monitoring system: real-time monitoring system temperature, vacuum, acquisition frequency 50ms / times.
Lyophilization process recipe storage function: can store 2000 group fixed or user-defined lyophilized formulation process.
PC remote monitoring system: remote monitoring equipment operating conditions, as far as monitoring distance 1.5KM.
Eutectic point test function (optional).
Process data recording system (Standard).
Calibration function: temperature and vacuum calibration ensures long-term accuracy of the measured values.
Lyophilized curve inquiry function (available temperature and vacuum degree curve, convenient process optimization and lyophilized effect verification).

Meets with GMP standard;
Meets with CE/ISO standard;
SIP+CIP is optional;
Material made by SS316L to meets with pharmaceutical standards.
Well documented included IQ/PQ/OQ/FAT and etc.

Dry Chamber

Vacuum vessel design standards, design pressure -0.1Mpa (SIP model as per Pressure container certificated *)
Polish SS304 or SS316L* material
Round corner design easy to clean
Cabinet vacuum leak rate 5*10-3Pa*m³/S
Roughness of chamber and door Ra≤0.4um
Insulation made of Polyurethane foam, thickness > 100mm
Door with two handle with lock (Extra pneumatic locking mechanism for SIP model)
Design as per GMP standard

Shelves

Shelves has high intensity and it reaches to 0.3Mpa in the pressure test which can be able to bear the long term usage.
Silicone oil circulating heating and cooling, temperature from +20°C to-40°C within 60min
Temperature control accuracy ±0.5°C (adjusted by PID, in balance)
Polish SS304 or SS316L* material
Roughness of chamber and door Ra≤0.4um
All carried out the leak test by helium mass spectrometer.
Design as per GMP standard

Easy to Use

Color touch screen,and PLC as control core ,system is stable and easy to operate; 32 groups of freeze drying date can be stored , every group can be set up 36 segments; with display freeze drying curves function and record data automatically; freeze drying data can be output by USB flash disk.

Automatic + manual control mode
User management
Recipe management
Data management
Process control
SCADA remote control system support computer and mobile
Alarm display system
Protection system

FD-P series Pharmaceutical freeze dryer lyophilizers hmi (16)

FD-P series Pharmaceutical freeze dryer lyophilizers hmi (2)

FD-P series Pharmaceutical freeze dryer lyophilizers hmi (13)

FD-P series Pharmaceutical freeze dryer lyophilizers hmi (5)

FD-P series Pharmaceutical freeze dryer lyophilizers hmi (1)

FD-P series Pharmaceutical freeze dryer lyophilizers hmi (10)

Auto CIP & SIP System

AISI SS316L material
Standard and wide -angle type and ball type
Everywhere can be cleaned in chamber
Intermittent cleaning, to insure cleaning pressure and effect, and save cleaning cost
Pulsatile negative pressure steam delivery
121℃ Steam disinfection
German GOETZE Valve
Pipeline material AISI SS316L
Pressure container certificated

Model & Specifications

MODEL	Unit	FD-P1	FD-P2	FD-P3	FD-P5
dry area	M²	1.15	2.16	3.24	5.2
Feed amount (material thickness 10mm)	L	10	20	30	50
Number of shelves	Qty	4+1	4+1	6+1	7+1
shelf size	cm	60*48	60*90	60*90	75*100
shelf spacing	mm	80	80	80	80
Temperature control range	℃	-50°C ~ +70°C	-50°C ~ +70°C	-50°C ~ +70°C	-50°C ~ +70°C
Water vapor condensation	Kg/B	≥20	≥40	≥60	≥100
Catch reservoir temperature	℃	≤-75	≤-75	≤-75	≤-75
cooling method	–	Water Cooling	Water Cooling	Water Cooling	Water Cooling
defrosting method	–	Water soaking	Water soaking	Water soaking	Water soaking
ultimate vacuum	pa	≤1	≤1	≤1	≤1
Installed power	kw	18	21	24	25
Dimensions (LWH)	cm	250110200	250130200	280120250	400150250
Φ22 vial volume	Pcs	2460	4608	6912	11648
Φ16 vial volume	Pcs	4788	8960	13440	22540
Total Weight	kg	1500	2600	2800	5000
Pure steam consumption	kgh	60	80	100	130
Injection water volume/pure water	1/min	60	75	90	120

Model	Unit	FD-P10	FD-P15	FD-P20	FD-P30	FD-P50
dry area	M²	10.5	15	20.2	29.7	51.3
Feeding amount (material thickness 10)	L	100	150	200	300	500
Number of shelves	Qty	7+1	10+1	11+1	11+1	19+1
shelf size	cm	99*152	99*152	121*152	150*180	150*180
shelf spacing	mm	80	80	80	80	80
Temperature control range	℃	-50°C ~ +70°C	-50°C ~ +70°C	-50°C ~ +70°C	-50°C ~ +70°C	-50°C ~ +70°C
Water vapor condensation	kgB	≥300	≥300	≥400	≥600	≥1000
Catch reservoir temperature	℃	≤75	≤-75	≤-75	75	≤75
cooling method	–	Water Cooling	Water Cooling	Water Cooling	Water Cooling	Water Cooling
defrosting method	–	Water soaking	Water soaking	Water soaking	Water soaking	Water soaking
ultimate vacuum	pa	≤1	≤1	≤1	≤1	≤1
Installed power	kw	58	80	96	120	150
Dimensions (LWH)	Cm	670180350	650×230×360	740210370	650240380	750240460
Φ22 vial volume	Pcs	22932	34398	45045	64449	111321
Φ16 vial volume	Pcs	42966	644149	84843	129789	224181
Total Weight	kg	7000	8000	11000	15000	26000
Pure steam consumption	kgh	200	230	280	380	500
Injection water volume/pure water	1min	160	200	230	280	400