BIO-TFF01 Small Tangential flow filter membrane ultrafiltration system

Small tangential flow

membrane ultrafiltration system

TFF Overview

Understanding tangential flow membrane ultrafiltration systems

Brief Introduction of Tangential flow filter (TFF)

Tangential flow filter (TFF), also known as cross flow filter (CFF), refers to the liquid flow direction and filter direction perpendicular to the filter form. Liquid flow creates a shear force on the surface of the filter media, reducing the stacking of the cake layer or gel layer, thus ensuring a stable filtration rate. According to the trapped particles or molecular size can be divided into microfiltration MF, ultrafiltration UF, nanofiltration NF and reverse osmosis RO. TFF technology is currently widely used in pharmaceutical, biological, chemical, food and beverage and environmental protection industries.

System Overview

The small tangential flow ultrafiltration system is a set of TFF devices developed by Labgeni for laboratory users. It is mainly applied to TFF research of small scale or pilot scale in laboratory. The system uses imported original box-type flat film package, can achieve microfiltration, ultrafiltration, to meet the needs of laboratory diversification.

System applications

• Cell collection, cell fluid clarification and filtration, recovery of antibodies or recombinant proteins
• Concentration and desalination of proteins, peptides or nucleic acids (DNA / RNA / oligonucleotides)
• Remove heat source or impurity molecules in the water, buffer, medium solution, equal volume of continuous dialysis
• System Features:
• Sample recovery rate is extremely high, and efficiently ensure protein activity
• Filtration speed is stable, can be continuous cycle of filtration, the film surface does not form a gel layer
• Easy to linear amplification, the maximum reduction time and cost from small scale preparation to large-scale production
• Universal stainless steel fixture, matching the major brands of imported original box-type film package, which can be installed  1 to 3 pieces at the same time
• Integrated design, easy to operate, according to different needs to choose the appropriate film fixture, peristaltic pump and film package
• Stainless steel stent + raw material tank, siphon feeding, easy  for  laboratory aseptic continuous operation

System Applications

• Cell collection, cell fluid clarification and filtration, recovery of antibodies or recombinant proteins
• Concentration and desalination of proteins, peptides or nucleic acids (DNA / RNA / oligonucleotides)
• Remove heat source or impurity molecules in the water, buffer, medium solution, equal volume of continuous dialysis
• System Features:
• Sample recovery rate is extremely high, and efficiently ensure protein activity
• Filtration speed is stable, can be continuous cycle of filtration, the film surface does not form a gel layer
• Easy to linear amplification, the maximum reduction time and cost from small scale preparation to large-scale production
• Universal stainless steel fixture, matching the major brands of imported original box-type film package, which can be installed  1 to 3 pieces at the same time
• Integrated design, easy to operate, according to different needs to choose the appropriate film fixture, peristaltic pump and film package
• Stainless steel stent + raw material tank, siphon feeding, easy  for  laboratory aseptic continuous operation

BIO-TFF01 System

It is suitable for small-scale TFF research in biological laboratories, such as biological separation, material concentration and protein solution purification.  Small size, exquisite, easy to disassemble.

BIO-TFF01 Basic Information

Model: BIO-TFF01 Process capacity: 0.1 ~ 20L/H Membrane form: 1~3 blocks,  0.1㎡imported box type flat membrane Power unit: Precision peristaltic pump 220V, Maximum flow 2L/MIN Raw material tank: Material AISI 316L, volume 2L

BIO-TFF05 System

Model: BIO-TFF05 Suitable for laboratory small-scale TFF studies Biological separation, material concentration and protein purification It is designed and manufactured by medical grade sanitary standard. It is small, exquisite and easy to assemble and disassemble

BIO-TFF05 Basic Information

• Model: BIO-TFF05
• Membrane form: 1 to 3 imported original box-type flat membranes of 0.5 square meters
• Membrane material: Biomax (polyethersulfone), PLC (modified cellulose), PVDF (polyvinylidene fluoride)
• Process capacity: 30 ~ 90L/H
• Power unit: Precision original peristaltic pump 220V, maximum flow 9L/min
• Raw material tank: material AISI 316L, volume 3.5L

Stainless steel fixture

Material AISI 316L 2 in 2 out sanitary quick interface with mirror polishing internal surface and sand blasting outside surface Fit 0.1 ㎡ imported box type flat membrane, optional brand Millpore, Sartorius and PALL

Power unit

LONGER peristaltic pump with reliable quality Maximum flow: 2L/MIN，Maximum pressure: 0.3Mpa Control: Start and stop control, direction control, speed control (0-5V, 0-10V, 0-, 10KHZ are optional)

Stainless steel bracket + raw material tank

Material AISI 316L Sartorius Outlet Filter Siphon feeding, easy lab aseptic continuous operation Tank volume: 1L, 2L, 3.5L, 5L, 10L, can be customized

Flat membrane packs

Filtration area: 0.1㎡, Ultrafiltration / microfiltration is optional Membrane material: Biomax, PLC  (modified cellulose), PVDF  (polyvinylidene fluoride) Optional brand: Millpore, Sartorius, PALL

Specification parameter

Optional items